miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22051 5' -50.8 NC_004927.1 + 41113 0.66 0.954784
Target:  5'- ---aCCaCACACCGGgggauuauaaaacgGGGGGUAGUGu -3'
miRNA:   3'- ccaaGG-GUGUGGUCa-------------UCCUCAUCAUc -5'
22051 5' -50.8 NC_004927.1 + 38710 0.68 0.909653
Target:  5'- ---gCCCGCGCCGugGGGAGccgAGUAGu -3'
miRNA:   3'- ccaaGGGUGUGGUcaUCCUCa--UCAUC- -5'
22051 5' -50.8 NC_004927.1 + 28399 1.13 0.002498
Target:  5'- cGGUUCCCACACCAGUAGGAGUAGUAGa -3'
miRNA:   3'- -CCAAGGGUGUGGUCAUCCUCAUCAUC- -5'
22051 5' -50.8 NC_004927.1 + 6114 0.67 0.943885
Target:  5'- gGGuUUCCCAU-CCAGUccucGGGGUAGUc- -3'
miRNA:   3'- -CC-AAGGGUGuGGUCAu---CCUCAUCAuc -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.