miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22052 5' -58.9 NC_004927.1 + 8439 0.67 0.512108
Target:  5'- cGCCCAuccAUCCU-CCACGGUCUgcUCGAu -3'
miRNA:   3'- -CGGGU---UAGGAgGGUGCCGGGguAGUU- -5'
22052 5' -58.9 NC_004927.1 + 22291 0.68 0.442643
Target:  5'- cGUCCGAcuuucggacgugcUUCUCCCACcGCCCCAUgAu -3'
miRNA:   3'- -CGGGUU-------------AGGAGGGUGcCGGGGUAgUu -5'
22052 5' -58.9 NC_004927.1 + 28547 1.07 0.00074
Target:  5'- cGCCCAAUCCUCCCACGGCCCCAUCAAc -3'
miRNA:   3'- -CGGGUUAGGAGGGUGCCGGGGUAGUU- -5'
22052 5' -58.9 NC_004927.1 + 70363 0.67 0.522266
Target:  5'- aGCCgGAUUCgaugCUUGCGGCCCCA-CAc -3'
miRNA:   3'- -CGGgUUAGGa---GGGUGCCGGGGUaGUu -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.