miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22074 5' -59.1 NC_004927.1 + 57918 0.66 0.594213
Target:  5'- --aCGCUCAUCGGAGuggUGCUGGCGa- -3'
miRNA:   3'- ucgGCGAGUGGUCUCu--GCGGCUGCaa -5'
22074 5' -59.1 NC_004927.1 + 20238 0.67 0.501437
Target:  5'- -uCCGCUCGCCGGGGACggacuuGCC-ACGg- -3'
miRNA:   3'- ucGGCGAGUGGUCUCUG------CGGcUGCaa -5'
22074 5' -59.1 NC_004927.1 + 71187 0.79 0.091035
Target:  5'- cGCCGCUCuACCaAGAGACGgCGACGa- -3'
miRNA:   3'- uCGGCGAG-UGG-UCUCUGCgGCUGCaa -5'
22074 5' -59.1 NC_004927.1 + 42712 1.05 0.001068
Target:  5'- uAGCCGCUCACCAGAGACGCCGACGUUg -3'
miRNA:   3'- -UCGGCGAGUGGUCUCUGCGGCUGCAA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.