miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22106 5' -52.9 NC_004927.1 + 37313 0.68 0.858908
Target:  5'- gGUGAcuacugaGGUGGcuccaacagUCGGagcGGAACCGACCa -3'
miRNA:   3'- gCACUa------CCACC---------AGCU---UCUUGGCUGGc -5'
22106 5' -52.9 NC_004927.1 + 75254 0.69 0.797115
Target:  5'- cCGUGGaGGgagucucGGUCGggGAGCUGGUCGa -3'
miRNA:   3'- -GCACUaCCa------CCAGCuuCUUGGCUGGC- -5'
22106 5' -52.9 NC_004927.1 + 50747 0.69 0.777829
Target:  5'- gGUGAUGGUGG-CGAu--GCUGGCgGu -3'
miRNA:   3'- gCACUACCACCaGCUucuUGGCUGgC- -5'
22106 5' -52.9 NC_004927.1 + 57569 0.72 0.652948
Target:  5'- aCGuUGAUGGgucGGUUGAcGGcCCGACCGa -3'
miRNA:   3'- -GC-ACUACCa--CCAGCUuCUuGGCUGGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.