miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22180 3' -54.5 NC_004927.1 + 4615 0.73 0.426745
Target:  5'- cUGCCGgaGUCgGUGGAGGUaaucuCCGACc -3'
miRNA:   3'- -ACGGCaaCAG-CACCUCCAaac--GGCUG- -5'
22180 3' -54.5 NC_004927.1 + 75542 0.71 0.558108
Target:  5'- aGUCGggGUCGgauggGGAGGg--GUCGGCu -3'
miRNA:   3'- aCGGCaaCAGCa----CCUCCaaaCGGCUG- -5'
22180 3' -54.5 NC_004927.1 + 50395 0.67 0.770951
Target:  5'- cUGCCGggagcgGUgGUGGuGGU--GCUGGCg -3'
miRNA:   3'- -ACGGCaa----CAgCACCuCCAaaCGGCUG- -5'
22180 3' -54.5 NC_004927.1 + 68015 0.66 0.836688
Target:  5'- cGCUGUUGgCGUccugauGGAGGacgUGCgCGACc -3'
miRNA:   3'- aCGGCAACaGCA------CCUCCaa-ACG-GCUG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.