miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22186 3' -52.6 NC_004927.1 + 74207 0.66 0.887581
Target:  5'- cGACCUGCUUgagCAGGCGGcGAUugcccguguucgcguAGCACg -3'
miRNA:   3'- -UUGGACGGGaa-GUUCGCC-UUG---------------UUGUG- -5'
22186 3' -52.6 NC_004927.1 + 23206 0.68 0.776344
Target:  5'- cAugCgGUCUUUguAGUGGAACAGCGCc -3'
miRNA:   3'- -UugGaCGGGAAguUCGCCUUGUUGUG- -5'
22186 3' -52.6 NC_004927.1 + 33645 0.69 0.734394
Target:  5'- uGCCUGCCCggUAAGgGuGACAGCGg -3'
miRNA:   3'- uUGGACGGGaaGUUCgCcUUGUUGUg -5'
22186 3' -52.6 NC_004927.1 + 25511 0.77 0.278367
Target:  5'- cGCC-GCCCUcggaGAGCGGGACGGCGCu -3'
miRNA:   3'- uUGGaCGGGAag--UUCGCCUUGUUGUG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.