miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22488 5' -44.1 NC_005068.1 + 43693 0.66 0.999991
Target:  5'- aGAUGCGAAAgagUUUGCAAAACaauuaauagCGGa -3'
miRNA:   3'- -UUGCGCUUUgcaAAACGUUUUGa--------GCC- -5'
22488 5' -44.1 NC_005068.1 + 17107 0.68 0.999883
Target:  5'- -uUGCGaAAGCGUg--GCAc-GCUCGGg -3'
miRNA:   3'- uuGCGC-UUUGCAaaaCGUuuUGAGCC- -5'
22488 5' -44.1 NC_005068.1 + 72074 0.68 0.999883
Target:  5'- cAUGC-AAAUGUUUUGCGGAACagUGGa -3'
miRNA:   3'- uUGCGcUUUGCAAAACGUUUUGa-GCC- -5'
22488 5' -44.1 NC_005068.1 + 10269 0.81 0.768047
Target:  5'- -uCGUGAAACaGUUUcGCAAAACUCGGu -3'
miRNA:   3'- uuGCGCUUUG-CAAAaCGUUUUGAGCC- -5'
22488 5' -44.1 NC_005068.1 + 10230 1.1 0.02927
Target:  5'- gAACGCGAAACGUUUUGCAAAACUCGGu -3'
miRNA:   3'- -UUGCGCUUUGCAAAACGUUUUGAGCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.