miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22542 3' -49.8 NC_005083.1 + 9558 0.66 0.999233
Target:  5'- cGUGUAGUUuuucAGGGUCGCGUUcGcCGCAu -3'
miRNA:   3'- -UACAUCAGc---UUCUAGCGUAA-C-GCGUu -5'
22542 3' -49.8 NC_005083.1 + 18876 0.66 0.998528
Target:  5'- -gGUGGUgauguucacauuuaUGAAGAUCaCAUUGUGCAGg -3'
miRNA:   3'- uaCAUCA--------------GCUUCUAGcGUAACGCGUU- -5'
22542 3' -49.8 NC_005083.1 + 109204 0.67 0.996576
Target:  5'- ---aAGUCGAAGcgCaugaaaaGCGUUGCGCAc -3'
miRNA:   3'- uacaUCAGCUUCuaG-------CGUAACGCGUu -5'
22542 3' -49.8 NC_005083.1 + 42770 1.05 0.024627
Target:  5'- gAUGUAGUCGAAGAUCGCAUUGCGCAAa -3'
miRNA:   3'- -UACAUCAGCUUCUAGCGUAACGCGUU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.