miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
2294 3' -59.9 NC_001408.1 + 2359 0.66 0.07877
Target:  5'- ----cGAGACGGGUCuuuggaGCGACCCCu-- -3'
miRNA:   3'- cgaguCUCUGCCCGG------UGCUGGGGcuu -5'
2294 3' -59.9 NC_001408.1 + 991 0.67 0.066896
Target:  5'- aGC-CAGGGacGCGGGUCugGcCCCUGGg -3'
miRNA:   3'- -CGaGUCUC--UGCCCGGugCuGGGGCUu -5'
2294 3' -59.9 NC_001408.1 + 4665 0.68 0.056757
Target:  5'- aGCUauggUAGAG-CGGGCCAacCGGCuCCUGAAa -3'
miRNA:   3'- -CGA----GUCUCuGCCCGGU--GCUG-GGGCUU- -5'
2294 3' -59.9 NC_001408.1 + 550 0.71 0.033376
Target:  5'- aGCgccgCAGuGAUGGGaucCCAgGACCCCGGGg -3'
miRNA:   3'- -CGa---GUCuCUGCCC---GGUgCUGGGGCUU- -5'
2294 3' -59.9 NC_001408.1 + 2094 1.07 0.00002
Target:  5'- uGCUCAGAGACGGGCCACGACCCCGAAg -3'
miRNA:   3'- -CGAGUCUCUGCCCGGUGCUGGGGCUU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.