miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
24126 3' -48.4 NC_005263.2 + 20425 0.67 0.948835
Target:  5'- -aAGGGCGCGCGcaGGAAUGgaugaUCGUc -3'
miRNA:   3'- agUUCCGCGUGC--UCUUAUaag--AGCAc -5'
24126 3' -48.4 NC_005263.2 + 20896 0.68 0.907439
Target:  5'- -gGAGGCGCACGGGAugacgccggAUgg-CGUGu -3'
miRNA:   3'- agUUCCGCGUGCUCUua-------UAagaGCAC- -5'
24126 3' -48.4 NC_005263.2 + 14624 0.7 0.823083
Target:  5'- gCAAGG-GCGCGAcGAAggg-CUCGUGa -3'
miRNA:   3'- aGUUCCgCGUGCU-CUUauaaGAGCAC- -5'
24126 3' -48.4 NC_005263.2 + 10088 0.71 0.792909
Target:  5'- gCGGGcaGCGCGuCGAGAAUGUUCgcgacCGUGa -3'
miRNA:   3'- aGUUC--CGCGU-GCUCUUAUAAGa----GCAC- -5'
24126 3' -48.4 NC_005263.2 + 6137 0.79 0.366214
Target:  5'- gUCGGuGCGCgaucgcaaaacACGAGAAUAUUCUCGUGc -3'
miRNA:   3'- -AGUUcCGCG-----------UGCUCUUAUAAGAGCAC- -5'
24126 3' -48.4 NC_005263.2 + 41947 1.09 0.004129
Target:  5'- cUCAAGGCGCACGAGAAUAUUCUCGUGu -3'
miRNA:   3'- -AGUUCCGCGUGCUCUUAUAAGAGCAC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.