miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
27717 5' -54.2 NC_005884.1 + 7737 0.66 0.641477
Target:  5'- --aGGCCAGGgUGGCCAgcagagUCCUCAa-- -3'
miRNA:   3'- uacUCGGUCCaACUGGU------AGGAGUgau -5'
27717 5' -54.2 NC_005884.1 + 43223 0.67 0.583765
Target:  5'- cGUGGGCCAGGaaaUUGGCCAgggUCCaaUCagGCUGa -3'
miRNA:   3'- -UACUCGGUCC---AACUGGU---AGG--AG--UGAU- -5'
27717 5' -54.2 NC_005884.1 + 17926 0.75 0.191201
Target:  5'- cUGAGCCAGGUUGACCAggcuggaUCCaaaGCUc -3'
miRNA:   3'- uACUCGGUCCAACUGGU-------AGGag-UGAu -5'
27717 5' -54.2 NC_005884.1 + 9755 1.05 0.001263
Target:  5'- gAUGAGCCAGGUUGACCAUCCUCACUAg -3'
miRNA:   3'- -UACUCGGUCCAACUGGUAGGAGUGAU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.