miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
28879 5' -49.7 NC_006146.1 + 43067 0.66 0.994512
Target:  5'- gGUUgagGGGUGCCAGCgACUGGc---- -3'
miRNA:   3'- aUAGaa-UCCACGGUCG-UGAUCacuua -5'
28879 5' -49.7 NC_006146.1 + 95071 0.67 0.987142
Target:  5'- -cUCgu-GGUGgCAGCugUGGUGGGg -3'
miRNA:   3'- auAGaauCCACgGUCGugAUCACUUa -5'
28879 5' -49.7 NC_006146.1 + 139464 0.69 0.973792
Target:  5'- -----gGGGUGCCuGCACUGGaGAAg -3'
miRNA:   3'- auagaaUCCACGGuCGUGAUCaCUUa -5'
28879 5' -49.7 NC_006146.1 + 48319 0.75 0.764788
Target:  5'- cGUCggAGGUGCUGGCGgUGGUGGGc -3'
miRNA:   3'- aUAGaaUCCACGGUCGUgAUCACUUa -5'
28879 5' -49.7 NC_006146.1 + 30418 1.05 0.016032
Target:  5'- uUAUCUUAGGUGCCAGCACUAGUGAAUa -3'
miRNA:   3'- -AUAGAAUCCACGGUCGUGAUCACUUA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.