miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
30651 3' -49.5 NC_006549.1 + 21671 0.67 0.993267
Target:  5'- aCCguagugCAuGGGA-GUGuCGUACGUGACGCc -3'
miRNA:   3'- -GGa-----GUuCUCUaUAC-GCGUGCACUGUG- -5'
30651 3' -49.5 NC_006549.1 + 99487 0.69 0.973357
Target:  5'- uCCUCGgcGGGGGUGU-CGgGCG-GACACa -3'
miRNA:   3'- -GGAGU--UCUCUAUAcGCgUGCaCUGUG- -5'
30651 3' -49.5 NC_006549.1 + 34221 0.71 0.933198
Target:  5'- aCCUCGAGAG---UGC-CGCGcGACGCg -3'
miRNA:   3'- -GGAGUUCUCuauACGcGUGCaCUGUG- -5'
30651 3' -49.5 NC_006549.1 + 91951 0.73 0.889761
Target:  5'- cCCUCAAGAuGAUAcgaGCGCACGgaagccuGCGCg -3'
miRNA:   3'- -GGAGUUCU-CUAUa--CGCGUGCac-----UGUG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.