miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
32002 5' -57 NC_006949.1 + 45301 0.66 0.621007
Target:  5'- uGCUUUGCGCgaugaUGUcgCCGCUGGuCGUCGu -3'
miRNA:   3'- -CGAGAUGCG-----GCAa-GGCGGUC-GCAGCc -5'
32002 5' -57 NC_006949.1 + 22704 0.67 0.577796
Target:  5'- uGCUCaACGguuCCGUggUUCGCCAGCGcguUCGa -3'
miRNA:   3'- -CGAGaUGC---GGCA--AGGCGGUCGC---AGCc -5'
32002 5' -57 NC_006949.1 + 28473 0.68 0.463862
Target:  5'- aCUCUGCGCgGgUCCGCguuCGGUGuuaUCGGg -3'
miRNA:   3'- cGAGAUGCGgCaAGGCG---GUCGC---AGCC- -5'
32002 5' -57 NC_006949.1 + 28513 1.12 0.000427
Target:  5'- aGCUCUACGCCGUUCCGCCAGCGUCGGu -3'
miRNA:   3'- -CGAGAUGCGGCAAGGCGGUCGCAGCC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.