miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
32008 5' -52.9 NC_006949.1 + 23354 0.66 0.792236
Target:  5'- uCCCGugugaaugugucuAACGGGC-AGGUaUCugGGUCGu -3'
miRNA:   3'- uGGGC-------------UUGUCCGuUCCA-AGugUCAGU- -5'
32008 5' -52.9 NC_006949.1 + 34693 0.66 0.751495
Target:  5'- uAUCCGAGCAaGCAAGGUUgGCGa--- -3'
miRNA:   3'- -UGGGCUUGUcCGUUCCAAgUGUcagu -5'
32008 5' -52.9 NC_006949.1 + 24625 0.75 0.276738
Target:  5'- uGCaCCGcuCAGGCAAuGGUUgGCGGUCAg -3'
miRNA:   3'- -UG-GGCuuGUCCGUU-CCAAgUGUCAGU- -5'
32008 5' -52.9 NC_006949.1 + 39212 1.08 0.001466
Target:  5'- cACCCGAACAGGCAAGGUUCACAGUCAc -3'
miRNA:   3'- -UGGGCUUGUCCGUUCCAAGUGUCAGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.