miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
4351 3' -59.6 NC_001720.1 + 37755 0.67 0.339699
Target:  5'- -cGUGGGGGA-CCUGGGcUUCCCCAUu -3'
miRNA:   3'- guUACCCCUUcGGGUCC-AGGGGGUGc -5'
4351 3' -59.6 NC_001720.1 + 7451 0.72 0.170188
Target:  5'- gUAGUGGGcGGAGCUUAGcUCCCCCuCGg -3'
miRNA:   3'- -GUUACCC-CUUCGGGUCcAGGGGGuGC- -5'
4351 3' -59.6 NC_001720.1 + 35734 0.8 0.04402
Target:  5'- ---cGGGGAuggcgAGUCCAGGUCCUCCAUGa -3'
miRNA:   3'- guuaCCCCU-----UCGGGUCCAGGGGGUGC- -5'
4351 3' -59.6 NC_001720.1 + 5982 0.96 0.002861
Target:  5'- cCAAU-GGGAAGCCCAGGUCCCCCACGu -3'
miRNA:   3'- -GUUAcCCCUUCGGGUCCAGGGGGUGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.