miRNA display CGI


Results 1 - 3 of 3 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
58 5' -52.5 AC_000003.1 + 23700 0.69 0.485112
Target:  5'- cACUguUCCCACUGA--CGCCCAAGc -3'
miRNA:   3'- uUGGucAGGGUGACUuuGCGGGUUUc -5'
58 5' -52.5 AC_000003.1 + 17130 0.7 0.43152
Target:  5'- aAGCC-GUCCCACUGuAGgGCUUGAAGg -3'
miRNA:   3'- -UUGGuCAGGGUGACuUUgCGGGUUUC- -5'
58 5' -52.5 AC_000003.1 + 23780 1.06 0.001258
Target:  5'- aAACCAGUCCCACUGAAACGCCCAAAGc -3'
miRNA:   3'- -UUGGUCAGGGUGACUUUGCGGGUUUC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.