miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
678 5' -53.5 AC_000018.1 + 5327 0.66 0.605546
Target:  5'- cUCGGCCGCGUgGCCuUUGGcACGg--- -3'
miRNA:   3'- -AGUCGGCGCGgUGGuAAUC-UGUaguu -5'
678 5' -53.5 AC_000018.1 + 35357 0.66 0.605546
Target:  5'- aCGGCCGCcCCGCCcauuUUAGcCGUUAAc -3'
miRNA:   3'- aGUCGGCGcGGUGGu---AAUCuGUAGUU- -5'
678 5' -53.5 AC_000018.1 + 18875 0.66 0.64071
Target:  5'- aUCAGUCGCugGCUACgGUcGGugGUCAc -3'
miRNA:   3'- -AGUCGGCG--CGGUGgUAaUCugUAGUu -5'
678 5' -53.5 AC_000018.1 + 158 0.66 0.605546
Target:  5'- aCGGCCGCcCCGCCcauuUUAGcCGUUAAc -3'
miRNA:   3'- aGUCGGCGcGGUGGu---AAUCuGUAGUU- -5'
678 5' -53.5 AC_000018.1 + 27656 1.06 0.001012
Target:  5'- cUCAGCCGCGCCACCAUUAGACAUCAAu -3'
miRNA:   3'- -AGUCGGCGCGGUGGUAAUCUGUAGUU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.