miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
7137 3' -62.5 NC_001895.1 + 21403 0.66 0.208046
Target:  5'- cGUgAGCUUacgcaGCGCGCCUuccUGCUGGuCAa -3'
miRNA:   3'- aCGgUCGGA-----CGCGCGGA---GCGACCuGU- -5'
7137 3' -62.5 NC_001895.1 + 21168 0.67 0.202563
Target:  5'- cUGCCGuGCugaugaCUGC-CGCCUCaaccggaaaGCUGGACAa -3'
miRNA:   3'- -ACGGU-CG------GACGcGCGGAG---------CGACCUGU- -5'
7137 3' -62.5 NC_001895.1 + 3823 0.69 0.142043
Target:  5'- cGCCAcUgaGCaGCGCCUCGCUGaGAUg -3'
miRNA:   3'- aCGGUcGgaCG-CGCGGAGCGAC-CUGu -5'
7137 3' -62.5 NC_001895.1 + 1361 0.73 0.067775
Target:  5'- aGCCAGCCacGC-CGaCCUCGCcUGGGCGa -3'
miRNA:   3'- aCGGUCGGa-CGcGC-GGAGCG-ACCUGU- -5'
7137 3' -62.5 NC_001895.1 + 7990 1.08 0.000095
Target:  5'- aUGCCAGCCUGCGCGCCUCGCUGGACAg -3'
miRNA:   3'- -ACGGUCGGACGCGCGGAGCGACCUGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.