miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
736 3' -55.2 AC_000020.1 + 12979 1.11 0.000306
Target:  5'- aGGCAUACCUUCCCGCCACAGCAGACAa -3'
miRNA:   3'- -CCGUAUGGAAGGGCGGUGUCGUCUGU- -5'
736 3' -55.2 AC_000020.1 + 30238 0.78 0.0939
Target:  5'- cGCAgGCUUUCCaGCCACAGCGGGCc -3'
miRNA:   3'- cCGUaUGGAAGGgCGGUGUCGUCUGu -5'
736 3' -55.2 AC_000020.1 + 11311 0.71 0.292579
Target:  5'- uGGCAcGCCUgCCCGCCAauguggAGCGGGg- -3'
miRNA:   3'- -CCGUaUGGAaGGGCGGUg-----UCGUCUgu -5'
736 3' -55.2 AC_000020.1 + 15408 0.68 0.405814
Target:  5'- uGGCAgcugcggugcgGCgCUUCCUaGCCACAGCgaugGGACGc -3'
miRNA:   3'- -CCGUa----------UG-GAAGGG-CGGUGUCG----UCUGU- -5'
736 3' -55.2 AC_000020.1 + 18046 0.66 0.52062
Target:  5'- gGGCAUaucAUCUUCCaCGCCAUGGUuGuCAa -3'
miRNA:   3'- -CCGUA---UGGAAGG-GCGGUGUCGuCuGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.