miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
7440 3' -57.4 NC_001902.1 + 8509 1.08 0.000245
Target:  5'- gGACGGAUCCCCCUAUAGGGUGGAGGAa -3'
miRNA:   3'- -CUGCCUAGGGGGAUAUCCCACCUCCU- -5'
7440 3' -57.4 NC_001902.1 + 13836 0.66 0.397908
Target:  5'- uAUGGAaCCCCCc--AGGGUgaaacccuccaaGGAGGAg -3'
miRNA:   3'- cUGCCUaGGGGGauaUCCCA------------CCUCCU- -5'
7440 3' -57.4 NC_001902.1 + 18932 0.67 0.334949
Target:  5'- aGGCGGggCUCCUUAaAGGuuagGGAGGAu -3'
miRNA:   3'- -CUGCCuaGGGGGAUaUCCca--CCUCCU- -5'
7440 3' -57.4 NC_001902.1 + 21967 0.67 0.326572
Target:  5'- uGAgGGAUUUCCUUGgaagcucGGGUGGGGGu -3'
miRNA:   3'- -CUgCCUAGGGGGAUau-----CCCACCUCCu -5'
7440 3' -57.4 NC_001902.1 + 22215 0.69 0.251358
Target:  5'- cGugGGAccaacgaccccUCCCCCaauaugaacuugUGUAGGGuUGGAuGGAg -3'
miRNA:   3'- -CugCCU-----------AGGGGG------------AUAUCCC-ACCU-CCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.