miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
8157 5' -55.3 NC_001978.2 + 5306 0.66 0.603609
Target:  5'- -aAgGGUcCGGCUCAgaaCGUUCGGGUUa -3'
miRNA:   3'- aaUgCCA-GUCGAGUa--GCGAGUCCGAc -5'
8157 5' -55.3 NC_001978.2 + 28912 0.68 0.429975
Target:  5'- -cACGGcUCAGCUCAUCaagggGCUUgAGGCg- -3'
miRNA:   3'- aaUGCC-AGUCGAGUAG-----CGAG-UCCGac -5'
8157 5' -55.3 NC_001978.2 + 12131 0.68 0.428977
Target:  5'- gUUGCGGUCGGCUCcggcacgguccuuAUCGggggCAcGGCUGg -3'
miRNA:   3'- -AAUGCCAGUCGAG-------------UAGCga--GU-CCGAC- -5'
8157 5' -55.3 NC_001978.2 + 25423 0.71 0.304668
Target:  5'- --cCGGUUcgGGCUCgacGUCGCcCAGGCUGa -3'
miRNA:   3'- aauGCCAG--UCGAG---UAGCGaGUCCGAC- -5'
8157 5' -55.3 NC_001978.2 + 5264 1.05 0.000945
Target:  5'- uUUACGGUCAGCUCAUCGCUCAGGCUGu -3'
miRNA:   3'- -AAUGCCAGUCGAGUAGCGAGUCCGAC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.