miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
8668 5' -43.4 NC_002229.2 + 2171 0.7 0.99938
Target:  5'- uGAGGGGUUUCGucucuggcauGUGCAGCAa--- -3'
miRNA:   3'- -CUUCCCAAGGC----------UAUGUCGUaauu -5'
8668 5' -43.4 NC_002229.2 + 5762 1.04 0.075415
Target:  5'- cGAAGGGUUCCGAUACAGCAUUAAa -3'
miRNA:   3'- -CUUCCCAAGGCUAUGUCGUAAUU- -5'
8668 5' -43.4 NC_002229.2 + 22807 0.7 0.999617
Target:  5'- --cGGGUUCUG-UACAGCGUUu- -3'
miRNA:   3'- cuuCCCAAGGCuAUGUCGUAAuu -5'
8668 5' -43.4 NC_002229.2 + 132950 1.04 0.075415
Target:  5'- cGAAGGGUUCCGAUACAGCAUUAAa -3'
miRNA:   3'- -CUUCCCAAGGCUAUGUCGUAAUU- -5'
8668 5' -43.4 NC_002229.2 + 136541 0.7 0.99938
Target:  5'- uGAGGGGUUUCGucucuggcauGUGCAGCAa--- -3'
miRNA:   3'- -CUUCCCAAGGC----------UAUGUCGUaauu -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.