miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
9371 3' -46.5 NC_002512.2 + 217779 0.66 0.999997
Target:  5'- gUCGccGggGUCgcGGCCGGcuggcGGAUCg -3'
miRNA:   3'- -AGUuaCuuUAGaaCCGGCUa----CCUAGa -5'
9371 3' -46.5 NC_002512.2 + 40776 0.66 0.999997
Target:  5'- gCGAUGAuggacuauguagAAUUUcgccUGGCCGAagaaUGGGUCg -3'
miRNA:   3'- aGUUACU------------UUAGA----ACCGGCU----ACCUAGa -5'
9371 3' -46.5 NC_002512.2 + 47727 0.69 0.999673
Target:  5'- cCGAUGGAAUCggGGCCGGUaaAUCc -3'
miRNA:   3'- aGUUACUUUAGaaCCGGCUAccUAGa -5'
9371 3' -46.5 NC_002512.2 + 195088 0.71 0.997513
Target:  5'- cUCGA-GggGUCgaGGCCGAggGGAUUg -3'
miRNA:   3'- -AGUUaCuuUAGaaCCGGCUa-CCUAGa -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.