miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
955 5' -52.1 NC_000902.1 + 31136 0.66 0.805812
Target:  5'- gCGGUAGCUguggCAUCCGGGcgGGU-UCAGg -3'
miRNA:   3'- -GUCGUCGA----GUAGGUCUuaCCGuAGUU- -5'
955 5' -52.1 NC_000902.1 + 31445 0.67 0.775066
Target:  5'- gAGCAGaucgaaCGUCCGGA-UGGCAUUAu -3'
miRNA:   3'- gUCGUCga----GUAGGUCUuACCGUAGUu -5'
955 5' -52.1 NC_000902.1 + 44095 0.69 0.664039
Target:  5'- cCGGCAGCUUcugCCAGAAcGGaUAUCAGg -3'
miRNA:   3'- -GUCGUCGAGua-GGUCUUaCC-GUAGUU- -5'
955 5' -52.1 NC_000902.1 + 13451 0.69 0.641035
Target:  5'- aCAGCAGUgagcgCGUCCAGAAaguucUGGCGa--- -3'
miRNA:   3'- -GUCGUCGa----GUAGGUCUU-----ACCGUaguu -5'
955 5' -52.1 NC_000902.1 + 25106 0.76 0.274969
Target:  5'- cCGGCAGCUCcggagCCGGAA-GGCAUCGc -3'
miRNA:   3'- -GUCGUCGAGua---GGUCUUaCCGUAGUu -5'
955 5' -52.1 NC_000902.1 + 25160 1.06 0.002664
Target:  5'- cCAGCAGCUCAUCCAGAAUGGCAUCAAc -3'
miRNA:   3'- -GUCGUCGAGUAGGUCUUACCGUAGUU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.