miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
969 5' -59 NC_000902.1 + 19255 0.66 0.475358
Target:  5'- gGGaUGCCGGacauuaccggacaaCUGCuGCG-GCACCUCAa -3'
miRNA:   3'- -CCaACGGUC--------------GACG-CGCgCGUGGAGUa -5'
969 5' -59 NC_000902.1 + 25071 0.67 0.43919
Target:  5'- aGGUugaUGCCauucuggaugAGCUGCuGgGCGCACCggCAg -3'
miRNA:   3'- -CCA---ACGG----------UCGACG-CgCGCGUGGa-GUa -5'
969 5' -59 NC_000902.1 + 16262 0.67 0.411048
Target:  5'- cGUUGUCAuGCUugGCGUGCGUACCagCAa -3'
miRNA:   3'- cCAACGGU-CGA--CGCGCGCGUGGa-GUa -5'
969 5' -59 NC_000902.1 + 4120 0.68 0.39292
Target:  5'- --aUGCCAGCgGCGCGCuCgGCUUCAc -3'
miRNA:   3'- ccaACGGUCGaCGCGCGcG-UGGAGUa -5'
969 5' -59 NC_000902.1 + 49003 0.7 0.29557
Target:  5'- uGUUGCCgaugAGgUGCGCGCGCAgCUgGc -3'
miRNA:   3'- cCAACGG----UCgACGCGCGCGUgGAgUa -5'
969 5' -59 NC_000902.1 + 49097 1.07 0.000534
Target:  5'- cGGUUGCCAGCUGCGCGCGCACCUCAUc -3'
miRNA:   3'- -CCAACGGUCGACGCGCGCGUGGAGUA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.