miRNA display CGI


Results 21 - 23 of 23 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12364 3' -56 NC_003324.1 + 51251 0.68 0.56671
Target:  5'- --cCGCUc-GUCAGGUUGAcGCGGCAGg -3'
miRNA:   3'- acuGCGGucUAGUCCAGCU-CGUCGUC- -5'
12364 3' -56 NC_003324.1 + 52375 0.66 0.631375
Target:  5'- aGACGCCGGccgccccgaAUCGGGcgguagaaggggcUCGAguugucuucgGCGGCAGg -3'
miRNA:   3'- aCUGCGGUC---------UAGUCC-------------AGCU----------CGUCGUC- -5'
12364 3' -56 NC_003324.1 + 52797 0.68 0.56671
Target:  5'- gGACGUguGGUCaAGGUCGAGUucuGGUc- -3'
miRNA:   3'- aCUGCGguCUAG-UCCAGCUCG---UCGuc -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.