miRNA display CGI


Results 1 - 5 of 5 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
21839 5' -50.5 NC_004831.2 + 15569 0.66 0.84349
Target:  5'- uGAUAGUAcCGGGGUG-GC-ACUUGcAGCc -3'
miRNA:   3'- -CUGUCGU-GUUCCACuCGaUGAAC-UCG- -5'
21839 5' -50.5 NC_004831.2 + 19784 0.67 0.8341
Target:  5'- aGGCAGC-UAAGGUuccAGCacaacaACUUGAGCg -3'
miRNA:   3'- -CUGUCGuGUUCCAc--UCGa-----UGAACUCG- -5'
21839 5' -50.5 NC_004831.2 + 35036 0.69 0.68188
Target:  5'- uGCAGCACGaacugucAGGUGcAGUUACUauAGCu -3'
miRNA:   3'- cUGUCGUGU-------UCCAC-UCGAUGAacUCG- -5'
21839 5' -50.5 NC_004831.2 + 26188 0.72 0.554594
Target:  5'- aGGCAGUACu-GGUGuGUauCUUGAGCg -3'
miRNA:   3'- -CUGUCGUGuuCCACuCGauGAACUCG- -5'
21839 5' -50.5 NC_004831.2 + 33320 1.11 0.001322
Target:  5'- gGACAGCACAAGGUGAGCUACUUGAGCc -3'
miRNA:   3'- -CUGUCGUGUUCCACUCGAUGAACUCG- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.