miRNA display CGI


Results 1 - 4 of 4 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22738 5' -52.9 NC_005091.1 + 47321 0.67 0.794992
Target:  5'- uGAUGAGcgGCUUgAuuUGGuugAGCACGUCg -3'
miRNA:   3'- gCUGCUCa-CGAAgU--ACC---UCGUGCAGa -5'
22738 5' -52.9 NC_005091.1 + 20796 0.68 0.764716
Target:  5'- gGACGAuUGU-UCA-GGAGCugGUCUu -3'
miRNA:   3'- gCUGCUcACGaAGUaCCUCGugCAGA- -5'
22738 5' -52.9 NC_005091.1 + 109 1.09 0.001782
Target:  5'- aCGACGAGUGCUUCAUGGAGCACGUCUa -3'
miRNA:   3'- -GCUGCUCACGAAGUACCUCGUGCAGA- -5'
22738 5' -52.9 NC_005091.1 + 57503 1.09 0.001782
Target:  5'- aCGACGAGUGCUUCAUGGAGCACGUCUa -3'
miRNA:   3'- -GCUGCUCACGAAGUACCUCGUGCAGA- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.