miRNA display CGI


Results 21 - 26 of 26 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
374 3' -61.5 AC_000011.1 + 5459 0.67 0.245683
Target:  5'- cGGgGGCGUAGGCG-UCC-GCgCCGCa -3'
miRNA:   3'- -UCgCCGCGUCCGUgAGGuCGaGGUGc -5'
374 3' -61.5 AC_000011.1 + 22923 0.67 0.250162
Target:  5'- cGCGGC-CAGGggguCGCUCUcguccagggucuaaAGCUCCGCu -3'
miRNA:   3'- uCGCCGcGUCC----GUGAGG--------------UCGAGGUGc -5'
374 3' -61.5 AC_000011.1 + 15810 0.66 0.25866
Target:  5'- cGGCucuuGGCGCGGGCGuaCCGGCgcgcgUCCGCc -3'
miRNA:   3'- -UCG----CCGCGUCCGUgaGGUCG-----AGGUGc -5'
374 3' -61.5 AC_000011.1 + 7085 0.66 0.272191
Target:  5'- -aCGGCcuuGUAGGCGCagCAGCccuucUCCACGg -3'
miRNA:   3'- ucGCCG---CGUCCGUGagGUCG-----AGGUGC- -5'
374 3' -61.5 AC_000011.1 + 8908 0.66 0.286286
Target:  5'- cGcCGGCGCgcaugaccaccuGGGCGaggUUgAGCUCCACGu -3'
miRNA:   3'- uC-GCCGCG------------UCCGUg--AGgUCGAGGUGC- -5'
374 3' -61.5 AC_000011.1 + 16046 0.66 0.290625
Target:  5'- uGGCGGCGUcGcGCAC-CCAGUacacguucccucgCCGCGg -3'
miRNA:   3'- -UCGCCGCGuC-CGUGaGGUCGa------------GGUGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.