miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
691 3' -55.7 AC_000018.1 + 3527 0.68 0.367851
Target:  5'- cGGGCaGGCUCCcaccaUGGGCAGGAGUUCGu -3'
miRNA:   3'- -UUUG-CCGAGGuc---GCUCGUUCUCGAGU- -5'
691 3' -55.7 AC_000018.1 + 5090 0.67 0.445804
Target:  5'- gGGACGGCUCCuG-GAGUAGGGaaUCAg -3'
miRNA:   3'- -UUUGCCGAGGuCgCUCGUUCUcgAGU- -5'
691 3' -55.7 AC_000018.1 + 9257 0.66 0.477328
Target:  5'- -cGCGGCgacgCCGGCGGcGCAcGGGCa-- -3'
miRNA:   3'- uuUGCCGa---GGUCGCU-CGUuCUCGagu -5'
691 3' -55.7 AC_000018.1 + 12673 0.69 0.332543
Target:  5'- cGAGCGGUUCCAGCGcGGCGccaacuuGGGgUCGu -3'
miRNA:   3'- -UUUGCCGAGGUCGC-UCGUu------CUCgAGU- -5'
691 3' -55.7 AC_000018.1 + 16115 0.66 0.498945
Target:  5'- --uCGGCucuUCCGGCGAGCAuaGGCg-- -3'
miRNA:   3'- uuuGCCG---AGGUCGCUCGUucUCGagu -5'
691 3' -55.7 AC_000018.1 + 21502 1.07 0.000555
Target:  5'- gAAACGGCUCCAGCGAGCAAGAGCUCAa -3'
miRNA:   3'- -UUUGCCGAGGUCGCUCGUUCUCGAGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.