miRNA display CGI


Results 1 - 6 of 6 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
7190 3' -49.8 NC_001900.1 + 28064 1.1 0.003163
Target:  5'- aCGUGUAGUCACCCGUGAAUACGUCGAc -3'
miRNA:   3'- -GCACAUCAGUGGGCACUUAUGCAGCU- -5'
7190 3' -49.8 NC_001900.1 + 42802 0.72 0.664835
Target:  5'- --cGUGGaUCugCCGUGggUugGUCa- -3'
miRNA:   3'- gcaCAUC-AGugGGCACuuAugCAGcu -5'
7190 3' -49.8 NC_001900.1 + 32756 0.72 0.709759
Target:  5'- -aUGUGGUUGCCCGccUGGAcUGCGUCGu -3'
miRNA:   3'- gcACAUCAGUGGGC--ACUU-AUGCAGCu -5'
7190 3' -49.8 NC_001900.1 + 32243 0.71 0.741559
Target:  5'- cCG-GUGGUUGCCCGUGAcgaccaucggcgaGUugGUCa- -3'
miRNA:   3'- -GCaCAUCAGUGGGCACU-------------UAugCAGcu -5'
7190 3' -49.8 NC_001900.1 + 34903 0.69 0.860123
Target:  5'- uCGUGUAGUCgACCCGcGccAGUGCGggGAu -3'
miRNA:   3'- -GCACAUCAG-UGGGCaC--UUAUGCagCU- -5'
7190 3' -49.8 NC_001900.1 + 5588 0.68 0.884464
Target:  5'- --cGUGGuUCACCCGcUGGAgcUGUCGGa -3'
miRNA:   3'- gcaCAUC-AGUGGGC-ACUUauGCAGCU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.