miRNA display CGI


Results 21 - 26 of 26 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
1343 5' -58.1 NC_001335.1 + 38283 0.67 0.494829
Target:  5'- uCCGCUCGGCCgGCcagcccgcgacUCGCCaaauacucGUCGGCu -3'
miRNA:   3'- uGGUGAGUCGGgUG-----------AGUGG--------CAGUCGc -5'
1343 5' -58.1 NC_001335.1 + 39623 0.69 0.354715
Target:  5'- --uGC-CAGCCCGCUUGCCGU-AGCGu -3'
miRNA:   3'- uggUGaGUCGGGUGAGUGGCAgUCGC- -5'
1343 5' -58.1 NC_001335.1 + 39850 0.66 0.535318
Target:  5'- cGCCGCaUCAGaucgccuCCCACUgcagGCCGUCGuGCGa -3'
miRNA:   3'- -UGGUG-AGUC-------GGGUGAg---UGGCAGU-CGC- -5'
1343 5' -58.1 NC_001335.1 + 41784 0.66 0.536373
Target:  5'- cAUCugUguGCCCGCcagcgUCcCCGUaCAGCGg -3'
miRNA:   3'- -UGGugAguCGGGUG-----AGuGGCA-GUCGC- -5'
1343 5' -58.1 NC_001335.1 + 46268 0.69 0.354715
Target:  5'- cGCCGCguugCGGCCgucgCGCUgACCGUgGGCa -3'
miRNA:   3'- -UGGUGa---GUCGG----GUGAgUGGCAgUCGc -5'
1343 5' -58.1 NC_001335.1 + 46764 0.67 0.445081
Target:  5'- -aCGC-CAGCCuCACggGCgGUCAGCGg -3'
miRNA:   3'- ugGUGaGUCGG-GUGagUGgCAGUCGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.