miRNA display CGI


Results 21 - 25 of 25 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22484 3' -46.3 NC_005066.1 + 141656 0.68 0.999756
Target:  5'- --aCGGcaGGAAGCGAAuCAGGgcuUCACCGu -3'
miRNA:   3'- cgaGCU--UCUUCGUUUuGUCU---AGUGGC- -5'
22484 3' -46.3 NC_005066.1 + 142168 0.67 0.999853
Target:  5'- uCUCGGAGAAGUAuacCAGAcuuuuaaugUCAUCGu -3'
miRNA:   3'- cGAGCUUCUUCGUuuuGUCU---------AGUGGC- -5'
22484 3' -46.3 NC_005066.1 + 154121 0.66 0.999951
Target:  5'- --aCGAGGAuuccGGCAGAAC-GAUCACg- -3'
miRNA:   3'- cgaGCUUCU----UCGUUUUGuCUAGUGgc -5'
22484 3' -46.3 NC_005066.1 + 161490 0.69 0.998506
Target:  5'- -aUUGAGGAaucccgcguuccucAGCAGAAUAGAUCGCa- -3'
miRNA:   3'- cgAGCUUCU--------------UCGUUUUGUCUAGUGgc -5'
22484 3' -46.3 NC_005066.1 + 163366 0.66 0.999986
Target:  5'- uUUUGAGGAAGUAGucACGGGcuuuuuugcgcguUCACCGc -3'
miRNA:   3'- cGAGCUUCUUCGUUu-UGUCU-------------AGUGGC- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.