miRNA display CGI


Results 21 - 25 of 25 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
22873 3' -49.1 NC_005137.2 + 58690 0.67 0.996014
Target:  5'- --cGCGU---UCGGAcaGUGGCGCCGcGUu -3'
miRNA:   3'- gcuCGCAaauAGUUU--UACCGCGGC-CG- -5'
22873 3' -49.1 NC_005137.2 + 116340 0.67 0.996014
Target:  5'- aCGGGCGUUUacGUCAAGcuuaaacgauuuGUGcGCGCUGa- -3'
miRNA:   3'- -GCUCGCAAA--UAGUUU------------UAC-CGCGGCcg -5'
22873 3' -49.1 NC_005137.2 + 1334 0.66 0.997605
Target:  5'- gGAGgaGUUa---AAGGUGGCGgCGGCg -3'
miRNA:   3'- gCUCg-CAAauagUUUUACCGCgGCCG- -5'
22873 3' -49.1 NC_005137.2 + 82948 0.66 0.998
Target:  5'- -aAGCG----UCGAGAUGGCacGCgCGGCa -3'
miRNA:   3'- gcUCGCaaauAGUUUUACCG--CG-GCCG- -5'
22873 3' -49.1 NC_005137.2 + 67725 0.65 0.998307
Target:  5'- gCGAGCGacgg-CGAGAccguguuggaguuUGGCGCCGa- -3'
miRNA:   3'- -GCUCGCaaauaGUUUU-------------ACCGCGGCcg -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.