miRNA display CGI


Results 21 - 26 of 26 are showing below:
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ID Location Perfect MFE.* RefSeq Acc. strand Start Position R_P_ratio# P value
Predicted miRNA align pattern
12349 5' -55.9 NC_003324.1 + 25491 0.71 0.354781
Target:  5'- cGCCUUCUA--CCCGaggaCGGUAGCGUCGc -3'
miRNA:   3'- uCGGAAGAUaaGGGC----GCCGUUGCGGU- -5'
12349 5' -55.9 NC_003324.1 + 7875 0.72 0.329975
Target:  5'- aAGCCU--UGUUCgCCGCGGCGGCaaaGCCc -3'
miRNA:   3'- -UCGGAagAUAAG-GGCGCCGUUG---CGGu -5'
12349 5' -55.9 NC_003324.1 + 3179 0.72 0.321205
Target:  5'- cGCUUUCUGUUCgCCucgaauggcaagaGCGGgAGCGCCGu -3'
miRNA:   3'- uCGGAAGAUAAG-GG-------------CGCCgUUGCGGU- -5'
12349 5' -55.9 NC_003324.1 + 46012 0.73 0.287156
Target:  5'- cAGCCUgcggcgucgcuugcuUCgcUUCCgaaGCGGCGGCGCCGa -3'
miRNA:   3'- -UCGGA---------------AGauAAGGg--CGCCGUUGCGGU- -5'
12349 5' -55.9 NC_003324.1 + 11573 0.75 0.213701
Target:  5'- cAGCCgaugCUGcUCCCGCGGCuccUGCCGg -3'
miRNA:   3'- -UCGGaa--GAUaAGGGCGCCGuu-GCGGU- -5'
12349 5' -55.9 NC_003324.1 + 23676 1.09 0.000852
Target:  5'- aAGCCUUCUAUUCCCGCGGCAACGCCAa -3'
miRNA:   3'- -UCGGAAGAUAAGGGCGCCGUUGCGGU- -5'
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Note:
      When operating RNAhybrid, the pipeline first calculates the perfect minimum free energy (Perfect mfe *) of a putative miRNA when the entire putative miRNA binds to a perfectly complementary target site, then it calculates the minimum free energy of RNA duplex (mfe of the miRNA/mRNA duplex), abbreviated as Rd_mfe. An alignment for which the Rd_mfe to its correspondent Perfect mfe ratio (R_P_ratio #) is more than 66% is regarded as a positive alignment as described by Krek et al. (21). The P_value is calculated by RNAhybrid.

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TDL, Institute of Biomedical Science, Academia Sinica, Taipei, Taiwan.
Copyright © 2007 TDL. All rights reserved.